Jie Shen, PhD

Jie Shen, PhDAssistant Professor

Department: Division of Epidemiology

Phone: (804) 628-2511

Email: jie.shen@vcuhealth.org

Address/Location:
One Capitol Square, 8th Floor, Room 824
Box 980101
830 E. Main Street
Richmond, VA 23219

Undergraduate Education

  • Fudan University, Shanghai, China, BS, Microbiology

Graduate Education

  • Fudan University, Shanghai, China, MS, Microbiology
  • The University of Texas Graduate School of Biomedical Sciences and MD Anderson Cancer Center, Houston, TX, PhD, Cancer biology

Post Graduate Education

  • Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Molecular Cancer Epidemiology, Tulane Cancer Center, Tulane University, New Orleans, LA

Research Expertise

  • Cancer biomarker
    Molecular cancer epidemiology

Keywords & Interest Areas

  • Molecular and genetic cancer biomarker, circulating cancer biomarker
  • Molecular profiling: metabolite profiling, microRNA profiling, DNA methylation profiling
  • Biomarker for cancer risk assessment and prediction of clinical outcome in cancer patients
  • Mitochondrial DNA and cancer, microRNA and cancer

Professional Affiliations

  • American Association of Cancer Research
    American Public Health Association 
    Gulf Coast Consortia

Selected Peer Reviewed Publications:

  • Zhao H, Shen J, Moore SC, Ye Y, Wu X, Zanetti KA, Esteva FJ, Tripathy D, Chow WH.  Breast cancer risk in relation to plasma metabolites among Hispanic and African American women. Breast Cancer Res Treat. 2019 Aug;176(3):687-696.
  • Shen J, Hernandez D, Ye Y, Wu X, Chow WH, Zhao H. Metabolic hormones and breast cancer risk among Mexican American Women in the Mano a Mano Cohort study.  Sci Rep. 2019 Jul 10;9(1):9989.
  • Shen J, Ye Y, Chang DW, Huang M, Heymach JV, Roth JA, Wu XF, Zhao H. Circulating metabolite profiles to predict overall survival in advanced non-small cell lung cancer patients receiving first-line chemotherapy. Lung Cancer. 2017 Dec; 114:70-78.
  • Shen J, Song R, Wan J, Huff C, Fang S, Lee JE, Zhao H. Global methylation of blood leukocyte DNA and risk of  melanoma. Int J Cancer. 2017 Apr; 140(7):1503-1509.
  • Zhao H, Shen J, Hodges TR, Song R, Fuller GN, Heimberger AB. Serum microRNA profiling in patients with glioblastoma: a survival analysis. Mol Cancer. 2017 Mar;16(1):59.
  • Zhao H, Heimberger AB, Lu Z, Wu X, Song R, Shen J. Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes. Oncotarget. 2016 Apr; 7(15):20486-95.
  • Shen J, Gopalakrishnan V, Lee JE, Fang S, Zhao H. Mitochondrial DNA copy number in peripheral blood and melanoma risk. PLoS One. 2015 Jun;10(6):e0131649.
  • Arenas M, Fowler R, Lucas A, Shen J, Rich T, Grubbs E,  Lee J, Scheet P, Perrier N, Zhao H. Preliminary whole-exome sequencing reveals mutations that imply common tumorigenicity pathways in MEN1 patients. Surgery, 2014 Dec;156(6): 1351-8.
  • Shen J, Hu Q, Schrauder M, Yan L, Wang D, Medico L, Guo Y, Yao S, Zhu Q, Liu B, Qin M, Beckmann MW, Fasching PA, Strick R, Johnson CS, Ambrosone CB, Zhao H, Liu S. Circulating miR-148 and miR-133a as biomarkers for breast cancer detection. Oncotarget. 2014 Jul; 5(14):5284-94.
  • Shen J, Behrens C, Wistuba II, Feng L, Lee JJ, Hong WK, Lotan R. Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput western array and immunohistochemistry. Cancer Res. 2006 Dec; 66(23):11194-206.

Back to Listing